At the University of Iowa, groundbreaking research is being conducted daily to tackle pressing issues that impact not only the state but also communities worldwide. From understanding the increase in cancer rates to exploring gene editing for rare diseases, researchers are striving to find solutions to vital questions. “Research changes lives,” says David Schwebel, UI vice president for research, emphasizing the university’s commitment to developing therapies and addressing community challenges with the aid of external funding.
In fiscal year 2026, the University of Iowa attracted $771.7 million in external funding, with $536 million allocated specifically for research and scholarly activities across more than 2,100 projects. The federal government was the primary source of this research support, contributing $295.8 million for diverse projects in medicine, public health, engineering, and more.
Collaborative Research Efforts
Notably, two UI research teams received prestigious National Institutes of Health (NIH) P-series grants, a first in over 20 years. These competitive awards unite experts from various fields to address complex health issues. One team, led by David Stoltz, is focusing on primary ciliary dyskinesia (PCD), a genetic disorder causing chronic respiratory issues. By leveraging Iowa’s expertise in cystic fibrosis, Stoltz’s team aims to develop gene-editing treatments to combat the root causes of PCD.
Another team from the Holden Comprehensive Cancer Center is targeting neuroendocrine tumors (NETs) with a $10.7 million NIH grant. Under the leadership of Dawn Quelle, James Howe, and Yusuf Menda, the research combines laboratory science, advanced imaging, and clinical trials to create new treatment strategies for NETs, which are increasingly diagnosed, especially in adults over 50.
Advancements in Brain Science
UI researchers are also expanding their understanding of the brain, with new funding aimed at studying its development and adaptation. Kai Hwang is investigating the mediodorsal thalamus to improve treatments for schizophrenia and ADHD. Additionally, Ece Demir-Lira’s work focuses on understanding why preterm children struggle with math, potentially improving educational outcomes.
Community-Focused Research
Research at UI also addresses the needs of rural communities. John Warren is working to enhance dental care access for low-income Iowans by placing dental trainees in community organizations. Meanwhile, Cara Hamann is leading efforts to reduce impaired driving fatalities through targeted prevention strategies. Katherine Hadlandsmyth is developing support resources for rural Veterans dealing with chronic pain.
These initiatives reflect the university’s dedication to improving health, education, and safety across Iowa and beyond, leveraging collaborative research to make a meaningful impact.
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