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<h2>Innovative mRNA Technique Targets Celiac Disease at Its Source</h2><br />
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Researchers at the University of Pennsylvania's Institute for RNA Innovation are pioneering a groundbreaking approach to tackle celiac disease. Through the use of messenger RNA (mRNA), scientists aim to suppress the immune response that leads to the symptoms of this autoimmune disorder.<br />
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Celiac disease, an autoimmune condition triggered by the ingestion of gluten, affects millions worldwide. The immune system's reaction to gluten in people with celiac disease causes damage to the small intestine, leading to various symptoms including abdominal pain, bloating, and nutrient malabsorption. Current treatments primarily focus on a strict gluten-free diet, which can be challenging to maintain and doesn't fully eliminate the risk of symptoms.<br />
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The innovative mRNA approach developed at Penn's Institute promises a new avenue for treatment by directly addressing the immune response. By using mRNA technology, researchers are able to instruct cells to produce proteins that can modulate or halt the immune reaction responsible for celiac disease symptoms.<br />
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This method leverages the same technology used in some COVID-19 vaccines, where mRNA is employed to instruct cells to produce a protein that elicits an immune response. In the case of celiac disease, the mRNA instructs cells to produce a protein that can potentially prevent the immune system from attacking the body's own tissues in response to gluten.<br />
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The research is still in its developmental stages, but early findings offer hope for a new form of treatment that could significantly improve the quality of life for those affected by celiac disease. Details and further updates on this research can be found through the <a href="https://www.instituteforrnainnovation.com/" target="_blank">Institute for RNA Innovation</a>.<br />
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